基因重组卡介苗活载体疫苗的研究进展

Advances in recombinant bacille calmette-guerin

基因重组卡介苗 (rBCG)是借助分子生物学技术 ,将外源基因导入BCG中构建而成的多价疫苗 ,rBCG可诱导长期的体液免疫和细胞免疫 ,初步的研究结果已显示出rBCG具有广阔的应用前景 。

Genetic recombinant Bacille Calmette-Guerin(rBCG)was constructed by introducing the extraneous gene into BCG.The long-term cellular and humoral response was induced by rBCG.The new results showed that rBCG was an effective,low-lost vaccine against many sorts of infective dieases and tumours.