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银屑病皮肤病损中免疫细胞及分子的作用 被引量:3

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摘要 近年来 ,随着银屑病研究的深入 ,有关细胞免疫在其发病机理中的研究获得较多的实验资料 ,特别是活化的T淋巴细胞与角朊细胞之间的相互作用 ,受到大多数学者的重视。本文就T淋巴细胞参与银屑病发病的证据 ,皮肤病损中T淋巴细胞的活化 ,T淋巴细胞亚群以及T淋巴细胞与表皮角朊细胞的相互作用 。
作者 孙延波
出处 《国外医学(免疫学分册)》 2001年第5期249-252,共4页 Foreign Medical Sciences(Section of Immunology Foreign Medical Sciences)
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  • 7Prinz JC,Gross B,Vollmer S,et al.T cell clones from psoriasis skin lesions can promote keratinocyte proliferation in vitro via secreted products.Eur J Immunol 1994;24:593 -598.
  • 8Austin LM,Coven TR,Bhardwaj N,et al.Intraepidermal lymphocytes in psoriatic lesions are activated GMP-17 (TIA-1)^+ CD8^+ CD3^+ CTLs as determined by phenotypic analysis.J Cutan Pathol 1998;25:79-88.
  • 9Nickoloff BJ,Wrone-Smith T.Injection of pre-psoriatic skin with CD4^+ T cells induces psoriasis.Am J Pathol 1999; 155:145-158.
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