孤独症近期预后状况的研究

The short-term outcome of autism children

目的 研究儿童孤独症的近期预后状况。方法 对 61例孤独症患儿进行 3～ 6年的追访 ,收集智商、社会适应商、症状变化、临床病史等资料 ,使用SAS统计软件做描述性统计分析。结果 在 61例孤独症患儿中 ,智力有缺损者为 3 7例 ( 76% ) ,6例 ( 1 2 % )处于边缘状态 ,仅有 6例( 1 2 % )智商超过 85分 ;社会适应能力有缺损者为 4 2例 ( 88% ) ,4例 ( 8% )属于边缘状态 ,仅 2例 ( 4% )达到正常水平。有 2 0 %～ 50 %的患儿孤独症症状持续存在 ,5%～ 1 2 %的患儿症状呈不同程度的加重。结论 提示儿童孤独症总体近期预后较差。

Objective The short term outcome of autistic children, and the biological, psychological and social factors related to the disorder were studied Methods Sixty one autistic children who were diagnosed in the Institute of Mental Health, Beijing Medical University were followed up for three or more years The data of children′s intelligence quotient (IQ), adaptive developing quotient (ADQ), clinical symptoms, history and social environment were gathered Descriptive statistics analyses were done with SAS software Results At the end of follow up, 76% of autistic children had intellectual impairment (IQ<70), and only 6 (12%) children′s IQ were 85 or over As to ADQ, 88% of the children were below normal level (ADQ<70), 8% in borderline (ADQ=84 70), and only 4% in normal range (ADQ≥85) Autistic symptoms sustained in 20% 50% of autistic children, and some symptoms aggravated in 5% 12% of children Conclusion It is suggested that the short term outcome of autism is not satisfactory generally