象限切除加腋淋巴结清扫加放射治疗早期乳腺癌

QUADRANT EXCISION PLUS REMOVAL OF AXILLARY LYMPH NODES AND IRRADIATION FOR EARLY CARCINOMA OF BREAST

探讨象限切除加腋窝淋巴结清扫及放射治疗早期乳腺癌的临床效果。对 6 6例行象限切除术加腋窝淋巴结清扫及放疗的乳腺癌患者 (观察组 )与 46例行标准根治术 (Halsted根治术 )加放疗的乳腺癌患者 (对照组 )比较 ,两组的生存率、局部复发率、远处转移率、生活质量和保留乳房的美观效果进行长期随访观察。结果 3、5、8年生存率 :观察组分别为 97 0 %、87 9%、71 2 % ,对照组分别为 97 8%、80 5 %、76 1% ,两组相比无显著差异 ;复发率 :观察组为 6 1% ,对照组为 4 3% ;远处转移率 :观察组为 16 7% ,对照组为 2 1 7% ,两组相比无显著差异 ;观察组保留乳房总优良率达 83 8%。结果表明 ,象限切除加腋窝淋巴结清扫及放射治疗早期乳腺癌疗效同Hal sted根治术 。

To evaluate the effect of local resection plus axillary dissection in the treatment of early breast cancer, 112 cases of early breast cancer were divided into 2 groups: quadrant resection plus axillary dissection group(66 cases) and Halsted′s method group(46 cases).Their survival rate, local recurrence rate, metastasis rate,cosmetic effect of breast were observed for a prolonged period. The results showed that the 3,5,8 year survival rates in the first group were respectively 97 0%,87 9% and 71 2%. The 3,5,8 year survival rates in the second group were respectively 97 8%,80 5%,76 1%. The rate of local recurrence was 6 1% in the first group and 4 3% in the second group.The metastasis rate of the first group was 16 7%,and that of the second group was 21 6%.In 83 8% of patients in the first group,the breasts retained a satisfactory cosmetic form.It suggested that similar to the Halsted's method,the quadrant resection plus axillary dissection method is an ideal method to treat early breast cancer.