经直肠彩色多普勒血流显像评价良性前列腺增生症的临床治疗效果

Clinical study on benign prostatic hypertrophy by transrectal color Doppler flow imaging

目的 探讨前列腺大小及内腺动脉血流动力学参数对良性前列腺增生症 ( BPH)疗效评估的意义。方法 2 4 8例 BPH患者随机分为 A、B两组 ,分别应用保列治和益气通淋冲剂进行治疗 ,采用经直肠彩色多普勒血流显像技术对治疗前、后的前列腺进行观察。结果 A、B两组前列腺厚径及上下径于治疗前、后差异均无显著性 ,P>0 .0 5 ;每组中的内腺动脉血流收缩期峰值速度 ( Vs)、舒张期血流速度 ( Vd)、阻力指数 ( RI)、血管内径( D)于治疗后均有显著下降 ( P<0 .0 5 ,P<0 .0 0 1)。结论 前列腺内腺动脉血流动力学主要参数可用于 BPH临床疗效的评估 ,而前列腺大小不能作为疗效观察指标 ,益气通淋冲剂治疗 BPH,其疗效与保列治相似 。

Objective To understand the significance of prostate size and the inner gland hemodynamic parameters in estimating the curative effect on benign prostatic hypertrophy (BPH).Methods Two hundred and forty eight cases were divided randomly into two groups A and B,receiving finasteride and yiqitonglin soluble granules respectively.The prostates were observed by transrectal color Doppler flow imaging pre and post treatment.Results There′s no noticeable difference in the longitudinal and transverse thickness of their prostates pre and post treatment between the two groups (P>0.05).The systolic velocity (Vs),diastolic velocity (Va),resistance index (RI)and arterial diameter (D) of inner gland were significantly decreased in each group.Conclusion The therapeutic efficacy on BPH can be evaluated by the hemodynamic parameters of inner gland,but the size of prostate can not;yiqitonglin soluble granules treating BPH has the same effect as finasteride does,and is fit to use widely due to its low price.