多聚白蛋白受体与乙型肝炎病毒复制及临床关系的探讨

RELATIONSHIP BETWEEN PHSA—R,REPLICATION OF HBV AND CLINIC

分折278例乙型肝炎病毒(HBV)感染者的多聚白蛋白受体(PHSA—R)与HBV部分复制指标及临床的关系。结果HBeAg阳性者PHSA—R阳性率明显增高(p<0.01),而抗-HBe反之。PHSA—R阳性率与抗一HBcIgM阳性率不尽平行。PHSA—R阳性者中SGPT、I I异常率高。研究表明PHSA—R与HBV复制有关。PHSA—R阳性者肝功能损害相对较重。

This paper analyses the relationship between polymerized human serum albumin receptor (PHSA-R(?), HBV replication marker and clinic in 278 cases of hepatitis B. The results showed that PHSA-R posistive rate increased markedly ( P<0.01 ) in patients with HBeAG. But it decreased in patients with anti-HBe. PHSA-R positive rates in patients with and without anti-HBe IgM didn't differ markedly. The abnormal rate of SGPT and II increased in patients with PHSA-R. These results suggested that PHSA-R was related to HBV replication. The liver functional damage was quite serious in patients with PHSA-R.