马鞍山市自然人群HBV感染血清流行病学及标志物模式研究

Sero-epidemiological and Mark Model Study of Natural Population HBV Infection in Maanshan City

采用ELISA对自然人群进行HBV感染的抽样检测分析 ,HBsAg、抗 -HBs、抗 -HBc阳性率分别为 1 3.57%、2 7.99%、1 6.80 %。总感染率为 44.2 7% ,有年龄组间的差异 ,无性别差异 ,城市高于农村。 1 0～岁和 40～岁是HBsAg阳性率的两个高峰 ,有年龄组间的差异 ,无性别差异 ,农村高于城市 ,标志物归类分析共有 1 8种组合模式 ,占感染者 5%以上的有 6种 ,单纯抗 -HBs阳性模式最多 ,占感染者的 32 .2 1 %。HBsAg携带者有 1 0种感染模式 ,其中2 9.2 9%伴有HBsAg阳性 ,且 86.79%分布在 2 0岁以下人群 ,有显著的性别差异和城乡差异。因此 ,城市曾有过广泛的HBV感染 ,现在具有一定的免疫力 ,农村目前HBV感染较城市严重 ,也缺乏免疫力。 2 0岁以下 ,尤其是在农村 。

persons from natural population was detected for HBV infection by ELISA. Positive rates of HBsAg, anti-HBs, anti-HBc were 13.57%, 27.99%, 16.80% respectively. Total HBV infection rate was 44.27%. There was significant difference in different age groups. No difference was observed between males and females. Positive rate in urban area was higher than that in rural area. There were two incidence peaks occurred in age group 10-15 and 40-50 respectively. 18 models were classified on basis of the detection results. There were six models which infections were more than 5% of all infections. Infections in anti-HBs model were maximum, which infections accounted for 32.21%. There were 10 HBsAg positive models, which infections accounted for 29.29%. Of them, 86.79% infections were people under age 20. There were significant differences between males and females, urban areas and rural areas. People in urban area had infected with HBV and obtained immunity. Infection in rural area was now more serious than that in urban area. Population whose age was under 20 was key population of HBV control.