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三氧化二砷的抗癌作用及其机制的研究进展 被引量：2

Role of Arsenic Trioxide Anti-tumor and Its Mechanism
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摘要 复习三氧化二砷对急性早幼粒白血病的作用机制 ,以及对慢性粒细胞白血病和淋巴瘤的可能机制 ,对胃癌的实验性研究 ,甚至更有用于预防冠状动脉再狭窄。促进细胞凋亡可能是三氧化二砷的最主要作用机制。 As a drug, arsenic trioxide is effectively used for acute promyelocytic leukemia clinically. Inducing tumor cell apoptosis is one of its major mechanism via bcl 2 gone. Therefore, arsenic trioxide is tried in experimental studies on some tumors, such as chronic myelocytic leukemia, lymphoma and gastric carcinoma, even on prevention of restenosis after percutaneous transluminal coronary angioplasty.
作者 赵智深 黄从新
机构地区 武汉大学人民医院心内科
出处 《中国药理学通报》 CAS CSCD 北大核心 2001年第5期492-494,共3页 Chinese Pharmacological Bulletin
关键词 三氧化二砷 细胞凋亡 白血病 抗癌作用 arsenic trioxide cell apoptosis tumor
分类号 R733.7 [医药卫生—肿瘤] R73－36 [医药卫生—肿瘤]
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共引文献741

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中国药理学通报
2001年 第5期

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