超声波和微波辐射催化缩酮反应

Catalysis of Ketol Reaction by Ultrasound and Microwave Irradiation

以十二水合硫酸铁铵作催化剂,相转移催化剂(PTC)PEG-400为助催化剂,利用超声波和微波辐射催化缩酮反应。以环己酮与乙二醇的缩合反应为探针反应,通过正交试验和单因素试验,考察了影响缩合反应的各种因素。确定缩合反应的最佳条件:环己酮与乙二醇摩尔比为1:1.5,十二水合硫酸铁铵0.007 5 mol,PEG-400 0.5 g,超声波辐射时间1 min,微波功率80 W,微波辐射时间5 min,产品产率达到90.6％。

The ketol reaction is catalyzed by ammonium ferric sulfate in the presence of PEG - 400 as a PTC under ultrasound and microwave irradiation. Using the condensation of cyclohexanone with ethylene glycol as probereac-tion, the effects on the condensation were investigated by orthogonal and single - factor experiments. The optimum conditions of condensation were as follows: the molar ratio of cyclohexanone to ethylene glycol 1:1.5, ammonium ferric sulfate 0.0075 mol, PGE - 400 0.5 g, ultrasonic irradiation time 1 min, microwave power 80 W, and mi-crowave irradiation time 5 min. The yield of product was up to 90.6 % .