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人用疫苗佐剂的研究现状 被引量：4

Development of Human Vaccine Adjuvants
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摘要 概述人用疫苗佐剂近年来的研究进展 ,主要涉及微生物来源佐剂、乳剂型佐剂、微粒型佐剂及合成佐剂等 ,介绍若干进入临床前和临床评价的新型佐剂产品 ,其中 QS2 1、ISCOMs、生物可降解聚合微球、Cp G ODN及 MF5 Development of human vaccine adjuvant s including microgram derived adjuvants, emulsions, particulate adjuvants and sy nthetic adjuvants were reviewed and several novel adjuvant candidates in pro-cl inical and clinical trials were introduced. QS21, ISCOMs, biodegradable polymer microspheres, CpG ODN and MF59 have broad prospects for clinical application as novel human vaccine adjuvants.
作者 管孝鞠 吴玉章
机构地区 第三军医大学全军免疫学研究所
出处 《药学进展》 CAS 2001年第4期207-210,共4页 Progress in Pharmaceutical Sciences
关键词 人用疫苗佐剂 微生物来源佐剂 生物可降解聚合微球 非离子阻断聚合物 合成佐剂 Human vaccine adjuvant Microgram derived adjuva nt Biodegradable polymer microsphere Nonionic block copolymer Synthetic adjuvan t
分类号 R94 [医药卫生—药剂学]
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参考文献15

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同被引文献85

  • 1靳玄烨,谢吉科,杨艳.脂质体制剂稳定性研究进展[J].河北医科大学学报,2004,25(6):374-376. 被引量：8
  • 2周红蕾,李春玲,王贵平,侯加法.脂质体作为疫苗免疫佐剂的应用研究进展[J].动物医学进展,2006,27(2):34-38. 被引量：7
  • 3陈庆华,瞿文.多肽、蛋白质药物的微球给药系统研究进展[J].国外医学（药学分册）,1997,24(3):129-133. 被引量：20
  • 4Ninomiya A, Riddell M A, Gidding H F. Intranasal administration of a synthetic peptide vaccine encapsulated in liposome together with an anti-CD40 antibody induces protective immunity against influenza A virus in miee[J]. Vaccine, 2002, 20(25 - 26) :3123.
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药学进展
2001年 第4期

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