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免疫肠内营养支持对胃肠道肿瘤患者术后的作用 被引量:13

Effects of postoperative immune enteral nutrient on immune function in patients with gastrointestinal cancer
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摘要 目的 :观察免疫肠内营养制剂茚沛 (IMPACT)对胃肠道肿瘤患者手术后的免疫调节作用。方法 :胃肠道肿瘤患者随机分为IMPACT组和能全素 (NUTRISON)组 ,在手术后进行肠内营养支持 10d ,肠内营养用量为 10 4 6kJ (2 5kcal) / (kg·d) ,术前和术后 11d测定血浆白蛋白、IgA、IgG、IgM、淋巴细胞计数、T淋巴细胞亚群分类。结果 :术后第 11d ,IMPACT组血浆白蛋白升高 (P <0 0 5 ) ,免疫功能指标较NUTRISON组有明显增强。结论 Objective:To elucidate the effect of postoperative immune enteral nutrient on immune function of gastrointestinal(GI) cancer patients.Methods:Sixty patients with GI cancer were divided into two groups: IMPACT group, NUTRISON group They were all given each enteral nutrition which provides 104 6 kJ (25 kcal)/(kg﹒d) for 10 days after digestive tract surgery plasma protein, IgA, IgG, IgM, total lymphocyte count, peripheral blood T lymphocyte subset were measured in the day before operation and on the 11 th postoperative day.Results:In IMPACT group, plasma protein were increased ( P <0 05) and the indexes of immune function were improved significantly. Conclusion:enteral nutrient IMPACT helps to ameliorate the immune function of postoprative GI cancer patients better than NUTRISON.
出处 《军医进修学院学报》 CAS 2001年第3期177-179,共3页 Academic Journal of Pla Postgraduate Medical School
关键词 胃肠肿瘤 肠营养 免疫治疗 IMPACT gastrointestinal neoplasms enteral nutrition immunotherapy
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