肝硬化患者肠系膜上动脉血流动力学的变化与腹水形成的关系

Changes of supperrior mesenteric artery hemodynanics in patients with hepatic cirrhosis affected ascites

采用彩色多普勒超声对 40例健康者 (对照组 )及 80例有 (或 )无腹水肝硬化患者 (肝硬化组 )进行肠系膜上动脉 (SMA)血流动力学测定。结果显示 :肝硬化组 SMA内径 (D)、血流速度 (v)、血流量 (Q)均较对照组显著升高 ,有腹水者较无腹水者高 ,SMA脉动指数 (SMA- PI)和阻力指数 (SMA- RI)均显著降低 (P<0 .0 1) ,尤以 SM-PI降低明显。肝硬化腹水组治疗前后上述各指标均无明显差异 (P>0 .0 5 )。提示肝硬化患者 SMA处于高动力循环状态 。

SMA hemodynamics indexes were measured by duplex Doppler ultrasound in 80 patients with hepatic cirrhosis(hepatic cirrhosis group),40 control subjects(control group) Results showed that the diameter (D),velocity (V),blood quantity (Q) of SMA were all increased in patients with hepatic cirrhosis and its were higher in those with ascites than those without ascites Both pulsatility indices (SMA PI) and resistance indices (SMA RI) were decreased (P<0 01) in patients with hepatic cirrhosis and SMA PI was lower significantly There were no significant changes in the indexes of SMA hemodynamice before and after medical treatment in patients with ascites This suggests that the SMA hemodynamics of patients with hepatic cirrhosis has changed,SMA play a major effect on the development of splanchnic hyperdynamic circulation and ascites