甲肝疫苗穴位注射治疗慢性乙型肝炎疗效的初步探讨

Curative effect of hepatitis A vaccine point injection in the treatment of chronic hepatitis B

[目的]探讨甲肝疫苗穴位注射治疗慢性乙型肝炎的疗效。[方法]采用临床对照试验方法,比较甲肝疫苗穴位注射(试验组)和口服干扰素(对照组)治疗慢性乙型肝炎的临床效果。[结果]试验组和对照组HBV·M(乙肝病毒标志物)的转阴率分别是:HBV-DNA转阴为60％和15.63％(P<0.005),HBeAg转阴率为41.18％和20.00％(P<0.05)。抗-HBe转阴率为21.21％和3.23％(P<0.05),抗-HBc转阴率为20.00％和4.41％(P<0.01),HBsAg转阴率为23.91％和0.00％(P<0.005)。[结论]甲肝疫苗穴位注射疗效优于口服干扰素,前者HBV·M转阴率及T淋巴细胞亚群均数均优于后者。

[Objective] To study curative effect of hepatitis A vaccine point injection in the treatment of chronic hepatitis B. [Methods] Apply clinical control method to compare clinical effect of hepatitis A vaccine point injection! experimental group ) and interferon per os ( control group ) in the treatment of chronic hepatitis B. [ Result] Negative rates of HBV. M for experimental group and control group were: HBV - DNA negative rates were 60% and 15.63% ( P < 0.005), HBsAg negative rates were 41.18% and 20.00% ( P < 0.05). Anti-HBe negative rates were 21.21% and3.23% ( P <0.05), anti - HBc negative rates were 20.00 % and4.41% ( P <0.01), HBsAg negative rates were 23.91% and 0.00% ( P < 0.005).[ Conclusion] Curative effect of hepatitis A vaccine point injection is better than that of interferon per os, HBV. M negative rate and average value of T - lymphocytes subgroup of the former are prior to the latter.