参芪五味子口服液的质量控制

QUALITY CRITERIONS FOR SHENQI WUWEIZI ORAL SOLUTION

目的 :建立参芪五味子口服液的质量检测标准。方法 :采用TLC对该口服液中的党参、五味子进行定性鉴别 ;以正丁醇 醋酸异戊酯 水 ( 4∶1∶5 )的上层液为展开剂 ,2 60nm为测定波长 ,对黄芪甲苷的含量进行定量研究。结果 :供试液在与对照液的TLC色谱相应位置上显相同颜色的斑点 ,黄芪甲苷平均加样回收率为 95 11% ,RSD =1 3 2 % ,点样量在 2～ 10 μg范围内线性良好 (r=0 9993 )。参芪五味子口服液中黄芪甲苷含量实测结果重复性好 ,RSD =3 3 7%。结论 :该方法简便快速 ,结果准确可靠 。

OBJECTIVE:To establish a method for quality control of Shenqi Wuweizi oral solution.METHODS:The main ingredient Codonopsine and Deoxyshizandrin were indentified by TLC.The content of astragalin was determined by TLCS,The developer was n butanol isoamy acetate aqua(4∶1∶5).The detective wavelength was 260 nm.RESULTS:The average recovery of Astragalin was 95.11%( RSD =1 32%).The linear range was 2 10 μg, r =0 9993.CONCLUSION:This method was simple,accurate and can be used for quality control of this oral solution