围产期孕妇支原体感染与产褥感染的关系

A Study on the Relationship between Puerperal Infection and Genital Mycoplasma Infection during Perinatal Period

目的 探讨围产期生殖道支原体感染与产褥感染的关系。方法 随机入选的 2 480例孕妇 ,采用支原体培养法检测围产期孕妇阴道解脲脲原体 (Uu)和人型支原体 (Mh) ,根据检测的结果分为支原体阳性组和支原体阴性组 ,随访观察两组产褥感染发生率。结果 支原体阳性组 110 0例 ,产褥感染发生率 4.4% (4 8/ 110 0 ) ,阴性组 1380例 ,产褥感染发生率 3.2 % (4 4/ 1380 ) ,两组产褥感染发生率无显著性差异 ;进一步分组研究发现Mh(+)Uu(+)亚组产褥感染发生率显著高于支原体阴性组 (11.7%对 3.2 % ,RR 3.7895 %CI 2 .13～ 6 .6 9,P <0 .0 5 )。结论 提示围产期生殖道支原体混合感染可能导致产褥感染。

Objective To explore the relationship between genital mycoplasma infection and puerperal infection during perinatal period.Methods Vaginal Ureaplasma urealyticum (Uu) and Mycoplasma hominis (Mh) were detected by the method of mycoplasma culture in 2480 pregnant women who were randomly enrolled into the study. They were divided into the positive group ( n =1100) and the negative group ( n =1380) based on the results of mycoplasma culture.Results Studies showed that the incidence rate of puerperal infection in positive group was 4.4% (24/1100) while that of the negative group, 3.2%. There was no difference between two groups. The further study showed that the incidence rate of puerperal infection in pregnant women with Uu(+)and Mh(+) was significantly higher than that in pregnant women with Uu( )Mh( ),(11.7% vs. 3.2%, RR 3.78, 95%CI 2.13 6.69, P <0.05).Conclusion Gnital mix mycoplasma infections during perinatal period may lead to puerperal infection.