摘要
目的 :明确双黄连粉针剂抗病毒作用谱及体外抗病毒作用机理。方法 :采用组织细胞培养法、染料摄入法检测双黄连粉针剂对各种病毒的作用 ,改变给药时间、途径 ,探讨双黄连粉针剂抗病毒作用环节。结果 :双黄连粉针剂具有明显抗流感病毒、呼吸道合胞病毒、腺病毒 型、单纯疱疹病毒 、 型、柯萨奇病毒 B3 、柯萨奇病毒 B4 、柯萨奇病毒 A16、新型肠道病毒 71型的作用 ;对脊髓灰质炎病毒 型、埃可病毒 6型、麻疹病毒、水泡性口炎病毒有一定的抑制作用 ;双黄连粉针剂与鱼腥草针剂相比 ,其抗病毒效果显著。结论 :双黄连粉针剂是一种较广谱的抗病毒针剂 ,抗病毒作用广泛。
Objective:To explicate effect spectrum and anti virus mechanism of Shanghuanglian in vitro .Methods:The inhibition effect of Shanghaunglian on various virus was observed with the method of tissue and cell culture,absorption of dye,and the anti virus effect of Shuanghuanglian Fenzhenji was studied by using medicine at different time.Results:Shanghuanglian had obvious anti virus effect on influenza virus,respiratory syncytical virus,Adenovirus Ⅲ,Herpes simplex virus Ⅰ,Ⅱ,Coxsackie virus,B 3,B 4,A 16 and had more distinct and stable effect than Houttuyniae Cordatae.It also had a little anti virus effect on poliovirus Ⅲ,ECHO virus 6,measles virus.Conclusion:Shuanghuanglian is a wide spectrum anti virus injection and has multimedia anti virus effect.
出处
《白求恩医科大学学报》
CAS
CSCD
北大核心
2001年第5期490-492,共3页
Journal of Norman Bethune University of Medical Science