期刊文献+

Tranilast及其在眼科的应用 被引量:8

Tranilast and its use in ophthalmology
下载PDF
导出
摘要 总结Tranilast的一般性质及其抗过敏、有抗纤维化和抑制新生血管形成等作用。回顾近年来Tranilast在过敏性结膜炎、春季结膜炎、PRK术后角膜上皮下浑浊、后发障、滤过泡疤痕化。 In this article, we first summarized the characteristics and anti allergy, anti fibrosis, anti neovascularization effects of tranilast. Then we reviewed the use of tranilast in fundmental research and clinical management of ophthalmic diseases, such as allergic conjunctivitis, vernal conjunctivitis, haze, after cataract, fibrosis of filtrating bleb, proliferative vitreoretinopathy and retinal choroidal neovascularization.
作者 曹阳 魏厚仁
出处 《眼视光学杂志》 CAS 2001年第3期186-188,共3页 Chinese Journal of Optometry & Ophthalmology
关键词 TRANILAST 药理学 眼疾病 过敏反应 纤维化 新生血管化 抗过敏药 tranilast/pharmacology eye diseases anti allergy anti fibrosis anti neovascularization
  • 相关文献

参考文献4

  • 1Lee E H,Invest Ophthalmol Vis Sci,1999年,40卷,2025页
  • 2Tripathi R C,Exp Eye Res,1994年,59卷,6期,723页
  • 3Liu J,Invest Ophthalmol Vis Sci,1994年,35卷,388页
  • 4Kogure F,临床医药,1993年,9卷,429页

同被引文献72

  • 1李金瑛,傅培,黎晓新.TGF-β_2反义寡核苷酸抑制抗青光眼术后滤过泡瘢痕的实验研究[J].眼科研究,2006,24(3):277-280. 被引量:12
  • 2Shah M, Foreman DM, Ferguson MW. Neutralisation of TGF - beta 1 and TGF-beta 2 or exogenous addition of TGF - beta 3 to cutaneous rat wounds reduces scarring [J]. J Cell Sci, 1995, 108(3):985-1002.
  • 3Ochiai H, Ochiai Y, Chihara E. Tranilast inhibits TGF-β1 secretion without affecting its mRNA levels in conjunctival cells[J]. Kobe J Med Sci, 2001, 47 (5):203- 209.
  • 4Oshima T, Kurosaka D, Kato K, et al. Tranilast inhibits cell proliferation and collagen synthesis by rabbit corneal and Tenon's capsule fibroblasts [J]. Curr Eye Res, 2000, 20(4):283-286.
  • 5Cordeiro MF. Role of transforming growth factor beta in conjunctival scarring[J]. Clin Sci(Lond),2003,104 (2):181-187.
  • 6Mietz H, Chevez-Barrios P, Feldman RM, et al. Suramin inhibits wound healing following filtering procedures for glaucoma[J].Br J Ophthalmol,1998, 82(7):816-20.
  • 7Saika S, Yanlanaka O, Baba Y, et al. Accumulation of latent transforming growth factor-beta binding protein-1 an d TGF beta 1 in cxtracclular matrix of filtering blcb and of cultured human subconjuncrival fibroblasts[J]. Graefes Arch Clin Exp Ophthalmol, 2001, 239(3):234-241.
  • 8Cordeiro MF, Gay JA, Khaw PT. Human anti-transforming growth factor-beta 2 antibody:A new glaucoma anti-scarring agent[J].Invest Ophthalmol Vis Sci, 1999,40(10):2225- 2234.
  • 9Shah M, Foreman DM, Ferguson MW. Neutralisation of TGF - beta 1 and TGF-beta 2 or exogenous addition of TGF - beta 3 to cutaneous rat wounds reduces scalring[J]. J Cell Sci, 1995,108(Pt3):985-1002.
  • 10Ochiai H, Ochiai Y, Chihara E. Tranilast inhibits TGF - β1 secretion without affecting its mRNA levels in conjunctival cells[J]. Kobe J Med Sci, 2001, 47 (5) :203-209.

引证文献8

二级引证文献11

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部