甲基磺酰胺合成工艺改进

Synthesis of Methanesulfonamide

介绍了硫酸二甲酯和硫代硫酸钠合成工艺的改进方法，采用水－二氯乙烷介质，不经精 制直接胺化，得到甲基磺酰胺。总收率（以硫代硫酸钠计）为 ６６％。产品纯度大于９８％。

This paper introduced the advanced process of methanesulfona- mide. Methanesulfonyl chloride is synthesized by PTC. It needn't purifi- cation and contacted with ammonia to methauesulfonamide. The yield as standard by sodium thicsulfate is 66 %. The purity is above 98 %.