期刊文献+

“遗传印记”现象的研究

Study of Genomic Imprinting
下载PDF
导出
摘要 “遗传印记”现象是由于子代体内来自父母双方的等位基因一方表达、另一方沉默造成的 .对该现象的研究是分子遗传学研究的新兴领域之一 .目前 ,通过一些研究方法 ,对“遗传印记”的分子机制已有一定的认识 ,随着对“遗传印记”研究的逐渐深入 ,必将深化人们对遗传和生命本质的认识。 The reason why there is the unique process of genomic imprinting in filial generation is that a gene on one chromosome is expressed, whereas its allele on the other chromosome is silenced. Genomic imprinting is being regarded as one of new field of genetics.At present,the molecular mechanisms of genomic imprinting were revealed to some extent by a few methods,with the development of researching,more and more answers about genomic and life will be found.
作者 岳强 刘主
出处 《韶关学院学报》 2001年第9期113-117,共5页 Journal of Shaoguan University
关键词 “遗传印记” 甲基化 印记者 绝缘子 分子遗传学 genomic imprinting methylation imprintor insulator
  • 相关文献

参考文献10

  • 1James McGrath,Solter D.Completion of Mouse Embryogenesis Requires Both the Maternal and Paternal Genome[].Cell.1984
  • 2Messing J,Grossniklaus U.Genomic imprinting in plants[].Results and Problems in Cell Differentiation.1999
  • 3Jo Peters,Stephante F Wroe,Chrostine A Well,et al.A cluster of oppositely imprinted transcripts at the Gnas locus in the distal imprinting region of mouse chromosome 2[].Proceedings of the National Academy of Sciences of the United States of America.1999
  • 4Denise P Barlow.Competition-a common motif for the imprinting mechanism?[].EMBO Journal.1997
  • 5Joanne L Thorvaldsen,Marisa S.Mothers Setting Boundaries[].Science.2000
  • 6Hark A T,Schoenherr C J,et al.CTCF mediates methylation-sensitive enhancer blocking activity at the H19/Igf2[].Nature.2000
  • 7Bell A C,Felsenfeld G.Methylation of a CTCF-dependent boundary controls imprinted expression of the Tgf2 gene[].Nature.2000
  • 8Andrew P Feinberg.Mendel stayed home[].The Inspector General.1999
  • 9Gabriel J M,Higgins M J,Gebuhr T C,et al.A model system to study genomic imprinting of human genes[].Proceedings of the National Academy of Sciences of the United States of America.1998
  • 10Bora E Baysal,Robert E Ferrell,Joan E Willett-broxick,et al.Mutations in SDHD, a Mitochondrial Complex II Gene, in Hereditary Paraganglioma[].Science.2000

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部