药物基因组学与个体化用药

Pharmacogenomics and Individualized Medication

药物基因组学是研究基因多态性与药物作用的多样性之间的关系的一门新兴学科。药物基因组学可以改善病人用药，提高用药的安全性和有效性，减少药物不良反应的发生，为个体化用药提供理论依据。本文介绍了药物基因组学的概念、研究内容和方法及其在临床个体化用药中的应用及意义。

Pharmacogenomics is an emerging scientific discipline studying the the association between genetic polymorphisms and the individual variations in response to therapeutics. It promises to increase the safety and efficacy for drug utilization,decrease the incidence of adverse drug reactions. Pharmacogenomics provides a theoretical basis for personalized medicine. The article introduced the concept, content, methods of pharmacogenomics and its applications in establishing clinical individualized medication.