沈阳细河水致突变性及其评价(Ames试验)

WATER MUTAGENICITY AND ASSESSMENT IN THE XIHE RIVER IN SHENLANG (AMES TEST)

为了解沈阳细河水是否存在致突变有机污染物,于1987年采集细河水样,浓集水中有机物并分为酸性、碱性和中性组份,用Ames试验平皿掺入法检测各样品的致突变性。结果表明:20-30ml(每皿)细河水所含有机污染物,毋需经过代谢活化,即可引起移码型和碱基置挨型的致突变作用。致变物主要在中性组份,其中又以强极性和中极性化合物为主。因此,对细河水的潜在危害必须高度重视。

In 1987, water was sampled in the Xihe River. The organic matters in water were dense, and divided into acidic, basic and neutral components in order to understand the mutagenic organic pollution. The mutagenicity of each samlpe was monitored by the method of plate incorporation of Ames Test. The results showed that the water organic pollution in the Xihe River had got mutagenicity of frameshift and base substitution without metabolic activation. The neutral components were the biggest among the three parts, and the neutral components mainly consisted of the strong polar compounds. Great attention must be paid to the potential risks the water of Xihe River in Shenyang may cause.