成都地区正常老中青年呼气峰流量探讨

Study of Peak Expiratory Flow in Normal Young, Middle-aged and Old Persons in Chengdu Area

目的 建立正常老中青年呼气峰流量 (PEF)的正常值范围及回归方程。方法 对 2 0～ 84岁 393例的正常老中青年测定了 PEF和 FVC、·V75、·V50 、·V2 5等常规肺通气功能指标。分别建立低龄组 (2 0～ 49岁 )和高龄组 (5 0～ 84岁 ) PEF的回归方程。结果 PEF以及 FVC、·V75、·V50 、·V2 5等测值均随年龄增长而下降。回归方程表明高、低龄组在男性 PEF与年龄呈负相关 (P<0 .0 0 0 0 1～ 0 .0 0 2 ,r=0 .32～ 0 .39) ,在女性 PEF与 FVC呈正相关(P<0 .0 0 0 1～ 0 .0 0 0 5 ,r=0 .32～ 0 .5 9)。 PEF与 ·V75呈高度正相关 ,高、低龄组在男性 r=0 .87～ 0 .94,在女性 r=0 .93～ 0 .96。 PEF的变异系数 (CV) ,除 70岁以上男女分别为 30 %与 2 7%外 ,其余各年龄组 CV为 16 %～ 2 4% ,处于正常值范围 ,确证数据可靠。结论 为 2 0～ 84岁的正常男女 PEF建立的正常值范围和回归方程 。

Objective To build the normal ranges and regression equations of peak expiratory flow (PEF) in normal young, middle aged and old persosn.Methods PEF, FVC,·V 75 ,·V 50 ,·V 25 were measured in 393 normal young, middle aged and old personss with the youngest aged 20 years and the eldest 84 years. Regression equations of PEF were built for younger group (20yr 49yr) and elder group (50yr 84yr) respectively.Results PEF,FVC,·V 75 ,·V 50 ,·V 25 were decreased with increase of age. The regression equations showed that both in younger and elder groups, PEF was negatively correlated with age in male ( P <0 0001 0 002, r =0 32 0 39) and positively correlated with FVC in female ( P <0 0001 0 0005, r =0 32 0 59). PEF was highly correlated to ·V 75 with r =0 87 0 94 in male and r =0 93 0 96 in female. The coefficient of variation (CV) of PEF was in normal range (16% 24%) for all age groups except male and female above 70 years old with CV of 30% and 27% respectively. This confirmed the data was reliable. Conclusion The normal ranges and regression equations of PEF constructed as a result of this study for normal humans of 20 84 years old can be put to use in clinical work and public health.