倍他乐克治疗慢性充血性心力衰竭86例疗效观察

The effect of Betaloc on CHF

目的 :观察β受体阻滞剂倍他乐克对慢性充血性心力衰竭 (CHF)的疗效。 方法 :将慢性CHF16 8例随机分为治疗组和对照组 ,两组年龄、心衰病程、原发病及心功能分级相似 ,具可比性 ,均给予常规抗心衰治疗 ,治疗组加用倍他乐克片剂 ,从小剂量 6 .2 5mg/d开始 ,缓慢加量至有效剂量或达 2 5～ 5 0mg/d。观察 12周后两组患者的NYHA心功能分级、左室射血分数、心排血指数、血压、心率、病死率及副作用等。结果 :治疗组较对照组NYHA心功能分级、左室射血分数、心排血指数均明显改善 ,血压、心率均明显降低 ,病死率下降 ,P <0 .0 5或 <0 .0 1。结论 :在常规抗心衰治疗的基础上加用倍他乐克治疗慢性CHF ,可明显改善患者心脏功能 ,提高患者生存率 ,且副作用小 ,值得临床推荐使用。

Objective: To observe the effect of Betaloc on chronic congestive heart failure (CHF). Methods: 168 cases chronic CHF were divided into treatment group and control group. There's no great significance in age, disease history, primary disease and heart function between the two groups. Both the groups were anti-heart failure treated ,and the treating group were used Betaloc. Results: The standard in treating group were all improved, while, blood pressure ,and heart rate were decreased ,(P<0.05,or<0.01). Conclusion: Betaloc improved heart function, has littele side effect.