卡介苗膀胱灌注后的并发症

Complication of Intravesical BCG Instillation for Bladder Cancer

报告自1983年1月至1990年7月95例膀胱癌以ECG膀胱灌注的并发症,其中严重并发症8例(8.42％),尿频尿痛尿急伴有血尿不能耐受而中止治疗1例,较严重血尿2例,附睾结核1例,前尿道周围肉芽肿及脓肿1例,前列腺肉芽肿1例,结核感染血行扩散1例,BCG肝炎1例。对其发生率、原因、预防与治疗进行了讨论。

Intravesical instillation of BCG was employed to prevent recurrence after surgical management in 95 cases with bladder cancer from January 1983 to July 1990. Complications occurred in 91 cases (95. 89%). Serious complications occurred in 8 cases (8. 42%) including serious hematuria in 2, epididymal tuberculosis in 1, periurethral granuloma and abscess in 11, prostatic granuloma in 1,BCG hepatitis in 1, tuberculous bloodstream dissemination inl. Instillation of BCG was discontinued in one case due to increased urinary frequency and urgency, dysuria and hematuria. The morbidity, cause and the ways to prevent and manage such complications are discussed.