摘要
应用消毒剂新洁尔灭、洗必泰醋酸盐,利凡诺作体外杀精子试验,其最低杀精浓度分别为0.25mg/ml、2.5mg/ml、7.5mg/ml。采用三种药物以最低杀精浓度总量8、10、14和16ml分别进行输精管结扎术时精囊灌注207例。临床观察表明:从精囊灌注后第一次尿中可排出精子3.6~60×10~6个,尿中精子总数在不同灌注量之间差异不明显,各药物组与生理盐水对照组无差异。术后第一次排精和术后1月取精液作常规检查者194例,未发现精子者分别为101例(52%)和169例(87.1%),其余虽有精子,但数量均在4×10~6/ml以内,并且三种药物分别灌注组的精子活力均完全消失。
The spermicidal potency of Bromo-geramine, Chlorhexidine diacetate and Rivanol was studied in vitro by Sander-Cramer test The minimun concentration of spermicidal activity were 0.25mg/ml, 2.5mg/ml and 7.5mg/ml respectively., 810, 14, 16ml of minimal concentration of these three disinfectants were injected into the seminal vesicle during 207 vesectomies. The results showedthat the numder of no sperm founded at first ejaculation and one month after vasectomy was 101 and 169 cases separately in 194 semen analyses, the sperm density was 4×10~6/ml in the others. The motility of sperm was totally disappeared.
出处
《男性学杂志》
CSCD
1991年第2期88-90,102,共4页