摘要
人类精浆中包含着大量的由支持细胞分泌的转铁蛋白(Transferrin,Tf)。本文采用单向免疫扩散法测定了50例生育男性、56例妻子流产的男性及143例不育男性精浆Tf含量。结果表明精子密度、活动力、活动率等皆与精浆Tf含量呈正相关;正常生育男性的精浆Tf含量与不育男性有高度显著性差异(P<0.01),而与妻子流产的男性则无明显差异(P>0.05)。精浆Tf含量测定有助于评价精子质量,可以作为反映支持细胞功能的特异性指标。
The seminal plasma transferrin concentration of 50 fertile men, 56 men whose wives have been aborted and 143 infertile men were measured by single radioimmunodiffusion. The results showed that seminal plasma transferrin concentration was positively related to sperm density, vitality, and motility. There was a significant difference between fertile and infertile men(P<0.01), but there was no significant difference between fertile men and the men whose wives have been aborted(P>0.05). So the determination of seminal plasma transferrin concentration may be considered as a specific function marker of Sertoli cells.
关键词
不育症
男性
转铁蛋白
支持细胞
Transferrin, Sertoli cells, Single radioimmuno-diffusion.
