良性甲状腺冷结节B超导向无水乙醇介入治疗的临床研究

Treatment of Benign Cold Thyroid Nodules by Percutaneous Ethanol Injectio nunder Guidance of Ultrasonography

目的 :探讨 B超导向经皮无水乙醇注射 ( PEI)治疗良性甲状腺冷结节的疗效及临床应用价值。方法 :PEI治疗 3 2例孤立性良性甲状腺冷结节 ,平均注射乙醇量为甲状腺结节治疗前容积的 1.2倍 ,分 4次进行。结果 :治疗后甲状腺结节容积显著减少 ,平均缩小 ( 5 6.5± 4 .0 ) %,有效率达 75 %,未见明显副作用。结论 :PEI是一种安全。

Objective:To evaluate the efficacy of percutaneous e thanol injection(PEI) guided by ultrasonography on the treatment of benign cold thyroid nodules. Methods:Thirty two cases of single benign cold thyroid nodules un derwent PEI. The total amount of anhydrous ethanol injected was approximate ly 1.2 times the volume of thyroid nodule before treatment, which was divided in four doses once a week.Results:After injection the volume of the nodules decreased markedly. The mean percentage of nodules shrinkage was 56.5%±4% and the efficacy rate was up to 75%. No obvious adverse effect was observed during therapy.Conclusion:PEI is an effective and safe therapy for benign cold thyroi d nodules as an alternative of surgery.