宫颈病变与人乳头状病毒感染的相关性及干预性预防的研究

Study of the Relationship Between Cervical Lesions and HPV Infection and the Interfered Prevention

目的 :探讨HPV感染与宫颈病变的关系。方法 :分析 1996年 1月 1日～ 1998年 6月 30日在法国马塞市Conception医院妇产科进行的 2 18例宫颈锥型切除术的病理结果与HPV感染情况。结果 :HPV总阳性率为 52 75% ,CIN 3的HPV阳性率最高 ,而CIN 2的HPV阳性率比CIN 1高。结论 :宫颈癌前病变与HPV感染极相关 ,宫颈癌者HPV感染的组织病理学诊断率低 ,应积极预防宫颈癌的发生。

Objective To evaluate the relationship between cervical lesions and HPV infection.Methods 218 cervical conizations have been done in the department of obstetrics and gynecology in Conception hospital in Marseille in France from January 1,1996 to June 30,1998.We studied the results of histologic and the positive rate for HPV of these conizations.Results The total positive rate for HPV was 52.3%.The positive rate was the highest in cervical intra epithelial neoplasia 3 (CIN 3),and higher in CIN 2 than in CIN 1.Conclusions HPV infection was strongly correlated with CIN.The positive rate for HPV by histologic diagnosis was low in cervical cancer.We should actively prevent the happening of the cervical cancer.