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巢蛋白及其功能 被引量:10

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摘要 巢蛋白 (nestin)是新发现的第Ⅵ类中间丝蛋白 ,其在胚胎前体细胞中成为最先表达的中间丝蛋白先驱。巢蛋白及其它中间丝成员相继表达的时空顺序与前体细胞朝终末分化方向发育为成熟细胞的过程相匹配 ;在正常细胞演变成肿瘤细胞过程中 ,巢蛋白又呈现返祖性表达。巢蛋白的表达受其内在的基因调控元件以及核激素受体 配基复合物、转录因子等调控。巢蛋白的功能与维持前体细胞正常的形态结构有关 。
作者 郭灵
出处 《解剖学研究》 CAS 2001年第3期229-231,共3页 Anatomy Research
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同被引文献90

  • 1郭灵,汪华侨,袁群芳,姚志彬.雄激素替代对去睾丸大鼠基底前脑NOS及Nestin阳性神经元的影响[J].解剖科学进展,2004,10(2):129-132. 被引量:3
  • 2郭灵,谢瑶,汪华侨,姚志彬.雄性大鼠去势后基底前脑NOS及Nestin阳性神经元的变化[J].解剖学研究,2004,26(1):6-8. 被引量:3
  • 3李鹂,涂自良,杜士明,黄良永,张小乔.氟西汀对实验性抑郁症大鼠抑郁行为及海马神经元再生的影响[J].医药导报,2006,25(4):280-282. 被引量:10
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