肝脏局灶性小占位的病灶/水信号强度比与病灶性质的相关性

Correlative Study Between Identifications and Lesion/water Signal Intensity Ratio (SIR) of the Small Focal Hepatic Lesions

目的 研究肝细胞癌、肝转移瘤、肝脏海绵状血管瘤和肝囊肿的病灶 /水信号强度比(SIR)与病灶性质的关系。方法 随机选择经确诊的肝细胞癌、肝转移瘤、肝血管瘤和肝囊肿病例共 92例 ( 144个病灶 )行前瞻性磁共振成像 ( 0 .5T)研究。计算 4种病灶的SIR并进行统计学分析。结果 在T1W图像上 ,肝血管瘤的SIR值与恶性肿瘤之间差异无显著性 (t=1.83 0 ,P =0 .0 71) ,肝囊肿的SIR值显著低于其它三者 (t =16.83 6,P <0 .0 1) ,以 1.2为界 ,诊断正确率为 94 % .于T2 加权像上 (TR =2 50 0ms) ,血管瘤的SIR值均显著高于恶性肿瘤 (P <0 .0 1) ,TE =12 0ms时 ,以 0 .6为界 ,区分血管瘤与恶性肿瘤 ,诊断正确率达 93 % ;以 0 .4 8为界 ,区分血管瘤与HCC ,诊断正确率为 97% .

Objective To determine the value of lesion/water SIR in characterizing the small focal hepatic lesions.Method Ninety two patients with 144 focal hepatic lesions were prospectively performed magnetic resonance imaging at 0.5T.Calculated lesion/liver SIR of hepatocellular carcinomas,metastases,hemangiomas and cysts.Result There was no significant difference between the values of SIR for hemangiomas and those for malignant lesions at T 1 weighted imaging(t=1.830,P=0.071).The values of the signal intensity ratios for cysts were significantly lower than those for the other three lesions at T 1 weighted imaging(t=16.836,P<0.01),a cutoff of 1.2 was 94% accurate.At T 2 weighted imaging(TR =2500ms) the values of the signal intensity ratios for hemangiomas were significantly higher than those for malignant lesions(P<0.01).A cutoff of 0.6 was 93%accurate to distinguish hemangiomas from malignant lesions at 120ms TE,and a cutoff of 0.48 was 97%accurate to distinguish hemangiomas from hepatocellular carcinomas.Conclusion SIR has the positive value for characterizing hepatic lesions.