依据药物作用的靶分子结构进行新药设计的方法

Structure-Based Drug Design

依据药物作用的靶分子结构进行新药设计 ,作为药物研究中的新方法使新药的研发过程正在从一种偶然性、经验性的过程逐渐走向一种合理的、科学的研发过程。作者在结合国内外有关文献基础上对这一方法的基本原理和基本过程进行综述。

Structure-based drug design,the new method and technologies in drug development has attracted a great deal of attention.It is switching the process of the drug discovery from the random and experiential way to a rational and reseanable way.The principles and procedures of the method were described in this paper.