马尾松松针化学成分的研究

STUDIES ON THE CHEMICAL CONSTITUENTS FROM PINENEEDLES OF PINUS MASSONIANA LAMB.

目的 研究松科植物马尾松 (P .massonianaLamb .)松针的化学成分。方法 利用色谱技术分离纯化 ,根据化合物的理化性质和光谱数据进行结构鉴定。结果 从马尾松针水煎液的正丁醇部位分离得到 3个化合物 ,分别鉴定为 :莽草酸 (shikimicacid ,1) ,cedrusin [( 7S ,8R) 3′ ,4 ,9,9′ 四羟基 3 甲氧基 7,8 二氢苯并呋喃 1′ 丙醇基新木脂素 ,2 ],massonianosideB [( 7S ,8R) 3 ,9,9′ 三羟基 3 甲氧基 7,8 二氢苯并呋喃 1′ 丙醇基新木脂素 4 O α L 鼠李糖苷 ,3 ]。结论 化合物 3为新化合物 ,化合物 1和 2是首次从本植物中分离得到。

AIM To study the chemical constituents of the pine needles of Pinus massoniana Lamb.. METHODS Various chromatographic techniques were used to separate and purify the chemical constituents. Their physico-chemical properties and spectral data were used to elucidate the structures. RESULTS Three compounds were isolated from the n-BuoH fraction of water-extracts. Their structures were identified as shikimic acid (1), cedrusin (2): (7 S ,8 R )-3′,4,9,9′,-tetrahydroxyl-3-methoxyl-7,8-dihydrobenzofunan-1′-propanolneoligan and massonianoside B (3): (7 S ,8 R )-3,9,9′-trihydroxyl-3-methoxyl-7,8-dihydrobenzofunan-1′-propanolneoligan-4- O -α- L -rhamnopyranoside on the basis of spectral data (IR, FAB-MS, 1HNMR , 13 CNMR , 1H- 1H COSY, 13 C- 1H COSY, DEPT, HMBC and ORD etc.). CONCLUSION Compound 3 is a new compound, while 1 and 2 were isolated from this plant for the first time.