2,2-二甲基-5-(2,5-二甲苯氧基)戊酸合成反应的研究

Study on Synthesis of 2,2-Dimethyl-5- (2,5-Dimethylphenoxy) Pentanoic Acid

在 1- (2 ,5 -二甲苯氧基 ) - 3-溴丙烷与异丁腈的烷基化反应中加入相转移催化剂 ,生成物不经分离 ,直接水解 ,总收率可达 78.2 %

If the phase transfer catalyst was added to the alkylation of 1-(2,5-dimethy lphenoxy)-3-bromopropane and isobutyronitrile,the intermediate was not separated and was direct hydroiyzed,the yields of product would reach to 78.2%.