期刊文献+

普罗帕酮终止阵发性室上性心动过速疗效观察 被引量:3

Effectiveness of propafenone for paroxysmal supraventricular tachycardia
原文传递
导出
摘要 目的观察普罗帕酮 (心律平 )终止阵发性室上性心动过速 (PSVT)的即时疗效及安全性。方法 3 7例 PSVT,静脉注射普罗帕酮70 mg,于 5分钟完成 ,观察 2 0分钟 ;未终止者重复用 70 mg,再观察 3 0分钟 ,仍未终止者再用 70 mg。用药前、后和 PSVT终止时 ,记录血压、心率及 12导联心电图。结果显效 75 .7% (2 8/ 3 7) ,有效 2 1.6% (8/ 3 7) ,总有效率 97.3 %。起效时间 1~ 5 5 (7.1± 2 .8)分钟。普罗帕酮平均累积量 10 5 mg。部分患者可出现轻度血压下降 ,P-R间期、QRS时限及 QTc间期延长 ,一过性 度 型窦房阻滞及头晕、恶心等副作用 ,未经处理逐渐消失。结论普罗帕酮静脉注射终止 PSVT有效、快速。 Objective To observe the clinical efficacy and safety of propafenone on paroxysmal supraventricular tachycardia (PSVT).Methods 37 patients with PSVT were injected with 70 mg propafenone intravenously in 5 minutes.The unrecovered patients in 20 minutes were injected with 70 mg propafenone intravenously again,who were given 70 mg propafenone intravenously once again if not controlled in late 30 minuted.Blood pressure,heart beat,12 lead electrocardiogram were recorded before and after use of drug.Results The significant effective rate was 77.5% and effective rate was 21.6% with overall effective rate of 97.3% and effective time of 1~55 (7.1±2.8) minutes.The average accumulated dose of propafenone was 105 mg.Some side effects were observed in part of patients,including slight reduction of blood pressure,P R interval.QRS wave and Q T interval prolonged,temporary type sino atrial block,vertigo and nausea,etc whice could vanish gradually if not treated.Conclusion Propafenone by intravenous injection can quickly contro PSVT with saftey and effectiveness.
出处 《中国综合临床》 北大核心 2001年第7期498-499,共2页 Clinical Medicine of China
关键词 普罗帕酮 心动过速 疗效 药物疗法 治疗 Propafenone Tachycardia Therapeutic effect
  • 引文网络
  • 相关文献

参考文献4

  • 1宋有城 浦介麟 等.静脉注射心律平对室上性心动过速疗效的再评价[J].中华心血管病杂志,1988,16(2):81-83.
  • 2伍子琳,顾复生.心律平治疗阵发性室上性心动过速的临床电生理研究[J].中华心血管病杂志,1990,18(3):160-163. 被引量:15
  • 3高诚 海滨 等.心血管疾病内科治疗学[M].北京:人民卫生出版社,1991.402-403.
  • 4李新华 刘键 刘良福 等.普罗帕酮严重反应5例.中国循环杂志,1999,14(4):200-200.

二级参考文献1

  • 1顾复生,北京医学,1986年,8卷,26页

共引文献17

同被引文献13

引证文献3

二级引证文献7

;
使用帮助 返回顶部