芬太尼与阿托品用于门诊无痛流产的临床观察

The clinical observation of Fentanyl with Atropine for ambulant analgesic abortion

目的 观察芬太尼与阿托品静脉注射在人工流产的镇疼效应。方法 自愿者Ⅰ -Ⅱ级ASA妇女 6 0例 ,分为A组单用芬太尼 (An =30 ) ,B组芬太尼与阿托品 30例 ,芬太尼 0 1mg,注速 2 0秒 ,观察镇疼效果按视觉模拟评分 (VAS)及用药后HR、RR、SpO2 、BP变化 ,及对人流综合征发生率和宫颈松驰情况。结果 AB两组镇疼满意 ,RR、SpO2 、BP无影响 ,无一例人流综合征发生 ,两组比较无统计学差异 (P >0 0 5 )。心率A组用药后下降明显 ,与B组比较差异显著 (P <0 0 1)。B组宫颈松驰优于A组 (P <0 0 1)。结论 阿托品与芬太尼用于门诊流产安全有效、价廉 。

Objective: To observe the analgesic effect of intravenous injection of Atropine with Fentanyl in induced abortion. Methods: 60 ASAⅠ Ⅱpregnant women were radomly divided into group A and B. Group A (n=30) was administrated only Fentanyl 0 1 mg/20 sec while group B (n=30) was administrated Fentanyl with Atropine. The results by visual analogue scale(VAS), the change of RR?SpO 2 and BP attack rate of induced abortion syndrome, and relaxation of tuba uterus.Results: Both group A and B satisfied the effect of analgesia. There were no changes of RR?SpO 2?BP . There was no induced abortion syndrome . There was no significant difference between the two groups (P>0 05 ).Heart rate of group A dropped distinctly after administration and there is significant difference compared with group B (P<0 01). Conclusion: Administration of Atropine with Fentanyl for induced abortion in ambulant is safe, effective and cheap,and patients can be easily accepted.