摘要
癌细胞原位分析有助于了解肿瘤发生发展过程中相关的基因、蛋白和信号分子等改变 ,可促进较精确的诊断方法、靶基因疗法以及肿瘤特异性标记物的发现。重点就癌细胞原位研究相关的一些新技术进展 ,如微切割、基因组学、遗传学和蛋白组学等技术 ,及其应用作一简要回顾 ,并对 2
Studying cancer cells in situ plays an important role in understanding the alterations of genes,proteins and signal transduction molecules whichis critical to cancer development and progression,and would promote the advancement of more precise diagnostics,therapeutic targets and biomarkers specific for human cancers.This review discuss mainly some advances in microdissection,genomics,genetics and proteomics,as well as their application in the study of cancer cell in situ,and also look forward to the progress in molecular biological research of cancer in the new century.
出处
《肿瘤防治杂志》
2001年第5期557-559,共3页
China Journal of Cancer Prevention and Treatment
关键词
癌细胞
原位
微切割
基因组学
蛋白组学
cancer cell
in situ
microdissection
genomics
proteomics
