鼻气道阻力测定与哮喘相关性的临床探讨

Clinical investigation of interrelation of nasal airway resistance surveyed and asthma

目的 :探讨鼻气道阻力测定技术在哮喘中的临床价值和哮喘的发病机理。方法 :35例哮喘患者和 32例健康者分别进行鼻气道阻力和呼吸阻抗测定。测量参数包括FLR75 ,FLR15 0 ,FLR30 0 ,RLR75 ,RLR15 0 ,RLR30 0和FEV1 。结果 :两组FLR15 0 ,FLR30 0 ,RLR30 0和FEV1 存在显著差异 ,而RLR15 0在两组间无显著差异。哮喘患者FEV1 与鼻气道阻力指标显著相关 ,其中与RLR30 0相关性最为显著。结论 :过敏性鼻炎既是哮喘的一个危险因素 。

Objective: It is to investigate the clinical significance of survey technique of nasal airway resistance in asthma and the mechanism of asthma. Methods: Nasal airway resistance and lung function of 35 asthma patients and 32 healthy volunteers were surveyed. The parameters included FLR75, FLR150, FLR300, RLR75, RLR150, RLR300 and FEV_1. Results: There were significant differences in FLR150, FLR300, RLR300 and FEV_1 between the two groups, but there were no significant differences in RLR150. In asthma patients, FEV_1 was significantly related to the nasal airway resistance parameters especially RLR300. Conclusion: Allergic rhinitis is not only the risk factor of asthma, but also the defense mechanism in the development of asthma.