摘要
目的 研究左旋咪唑致脱髓鞘脑病的CT、MRI表现特点 ,探讨CT、MRI的诊断价值。方法 分析 3 5例左旋咪唑致脱髓鞘脑病的CT、MRI及临床资料。结果 本病在CT、MRI上显示为双侧脑室周围及额、顶、枕、颞叶白质区有多发病灶 ,CT为低密度影 ,MRI为长T1长T2信号 ,很少有占位效应。MRI的影像学诊断率明显高于CT。本病的主要临床表现为急性或亚急性起病的弥漫性脑损害的症状和体征。结论 CT、MRI能为左旋咪唑所致脱髓鞘脑病的临床诊断提供重要诊断信息 ,且MRI优于CT。与有相似影像表现病变的鉴别应紧密结合临床资料 ,仅凭CT、MRI表现有一定局限性。
Objective To study CT and MRI features of levamisole induced demyelinating encephalopathy(LIDE),discuss the diagnostic value with CT and MRI. Methods The clinical,CT and MRI data were analysed in 35 patients with LIDE. Results CT and MRI showed multiple white matter lesions scattered in frontal, parietal, occipital, temporal and periventricular area of the disease LIDE.The lesions were low density on CT and long T1,T2 wighted signals on MRI. Mass effect was rarely showed. Diagnostic rate of MRI was higher clearly than that of CT. The main clinical manifestation of the disease was acute or subacute mental and neurologic disorder due to diffuse cerebral lesion. Conclusion CT and MRI can provide important information for clinical diagnosis of LIDE.MRI is superior to CT.
出处
《中国医学影像技术》
CSCD
2001年第10期941-942,共2页
Chinese Journal of Medical Imaging Technology
关键词
左旋咪唑
脱髓鞘脑病
磁共振成像
CT
诊断
Levamisole
Demyelinating encephalopathy
MRI
Tomography, X ray computed