中医药防治胃肠菌群与毒素移位理论与方法的探讨

Exploration of TCM Prevention and Treatment of Gastrointestinal Flora and Theory and Method of Toxin Displacement

肠道菌群及其毒素的移位是引起多器官功能障碍综合征 (MODS)的原因之一 ,而肠道缺血、菌群失调、解剖与生物屏障破坏、肠道内有关物质缺乏是肠道菌群及其毒素的移位的基础。结合中医理论、文献资料和临床实践 ,提出通腑泻浊、急下存阴 ,活血化瘀、清热解毒 ,补脾益气、泻浊解毒三大法则防治肠道菌群及其毒素的移位 。

Intestinal flora with displacement of its toxin is one of the reasons to cause multiple organ disturbance syndrome(MODS).Intestinal ischemia,flora imbalance,destruction of anatomical and biological barrier and lack of related substances in the intestine are the basis for displacement of its toxin.In integration of Chinese medical theory,literature and clinical practice,this article puts forward the three methods to dredge the hollow organs,expel the turbidity,promote purgation and remain yin,to activate blood,disperse stagnation,clear away heat and dissolve toxins,and to tonify the spleen,benefit qi,expel the turbidity and dissolve toxins for prevention and treatment of intestinal flora and displacement of its toxin,so as to hinder or reduce occurrence of MODS.