偏最小二乘法测定安痛定注射液中3组分含量

Determination of Three Compenents in Antodine Injection With Partial Least Square Method

目的 :测定安痛定注射液3组分的含量。方法 :采用偏最小二乘法 ,以0 1mol/L氢氧化钠溶液为溶媒。结果 :平均回收率氨基比林为99 7 % (RSD=0 67 % ) ,安替比林为99 1 % (RSD=0 76 % ) ,巴比妥为99 5 % (RSD=0 72 % )。结论 :本方法操作简便、快捷、重现性好。

OBJECTIVE:To determine aminophenazone,phenazone and barbital in antodine injection.METHODS:Taking 0.1mol/L NaOH as solvent,the detection data was caculated with partial least square method.RESULTS:The average recoveries were 99.7% for aminophenazone(RSD=0.67%),99.1% for phenazone(RSD=0.76%) and 99.5% for barbital(RSD=0.72%).CONCLUSION:The method is simple,rapid and good in repeatability.