比索洛尔在静息时发生心绞痛中的应用

Role of Bisoprolol in Treatment of Resting Angina

目的 评价比索洛尔 (博苏 )在控制静息时发生心绞痛中的价值。方法 对 16例按 1979年WHO冠心病标准诊断为静息时发生心绞痛的患者在常规使用硝酸甘油、利尿剂或地高辛基础上给予比索洛尔治疗 ,并与美多心安治疗组对照。治疗前后行Holter检查 ,治疗结果按临床心绞痛症状消失情况和HoIter检查缺血事件减少程度分为显效、有效、无效三组。结果 比索洛尔组显效和有效共 14例 (87 5 % ) ,美多心安组显效和有效共 10例 (5 5 5 6 % ) ,比索洛尔控制卧位型心绞痛有明显疗效 (P <0 0 5 )。结论 比索洛尔联合使用硝酸甘油。

Objective To assess the value of bisoprolol in controlling resting angina. Methods 16 patinents diagnosed as resting angina by administered bisoprolol in addition to the routine therapy of glyceryl trinitrate, diuretics or digoxin and compared with the controls taking metoprolol. Holter test was carried out before and after the treatment. Results 14 cases (87 5%) in the bisoprolol group achieved excellent or good results and 10 cases (55 56%) in the group with metoprolol showed excellent or good results. Bisoprolol had significant effect on resting angina. Conclusion Bisoprolol combined with glyceryl trinitrate, diuretics or digoxin in effective in controlling lying in bed angina.