腰蛛网膜下腔持续引流注药治疗重症颅内感染40例分析

Analysis of Treatment of 40 Cases of Severe Intracranial Infections by Continuous Drains through lumbar Subarachnoid Catheter with Administrations of Antibiotics

目的 研究一种治疗重症颅内感染的新方法。方法 选择重症颅内感染 40例 ,随机分组进行间断腰穿注药及蛛网膜下腔置管持续引流注药治疗 ,对比疗效。结果 蛛网膜下腔置管持续引流注药治疗具有脑脊液药物浓度高 ,能有效控制颅内压 ,减轻脑膜刺激 ,缩短感染治疗住院日 ,具有良好效果。结论 一旦发生手术及创伤后颅内感染 。

Objective To investigate a new therapeutic method of severe intracranial infection(SII)\ Methods 40 cases of SII were divided randomly into two groups and treated respectively by intermittent lumbar puncture with administrations of antibiotics(LPA)or by continuous lumbar subarachnoid catheters drain with administrations of antibiotics(LSACA).Results\ LSACA treatment was more effective because it has a higher drug concentration in cerebrospinal fluids,a better control of intracranial pressure,a smaller stimulation of meninges and a shorter periods of hospitalization.Conclusions\ These results demonstrate that LSACA treatment is a preferential choice in the cases of intracranial infection following neurosurgery or cerebral trauma.