城市居民非胰岛素依赖型糖尿病危险因素的病例对照研究

Case Control Study on the Risk Facotrs of NIDDM in City

目的 了解城市居民NIDDM的危险因素 ,制定针对高危人群及全人群的干预措施。方法 对 12 6例NIDDM患者进行 1:1配对病例对照研究 ,采用条件Logistic回归模型分析。结果 糖尿病家族史 (OR =3 713)、高脂血症 (OR =3 2 92 )、体重指数 (OR =3 0 5 5 )、高血压、饮食习惯 (喜荤食、喜甜食 )等是NIDDM的主要危险因素。结论 遗传在NIDDM发病中起重要作用 ,肥胖、高血压、高血脂症在NIDDM的病因中为最受重视的环境危险因素。应对城市居民NIDDM高危人群及全人群提倡合理膳食 ,采用适度活动 ,控制体重和血压 ,加强对社区一般人群糖尿病知识的宣传 ,提高居民的自我保健意识。

Objective To understand the risk factors of non-insulin dependent mellitus(NIDDM)in urban area and to provide the intervention strategy for high risk population and whole population.Methods The one to one matched case control study of 126 NIDDM patients are investigsted,the data are analyzed by conditional logistic regression model.Results It shows that family history of diabetes(OR=3 713),hyperlipoproteinemia(OR=3 292),body weight index(OR=3 055),hypertension,diet habit(favor of meat and sweet diet)are the main risk factors of NIDDM.Conclusion The results suggest that the heredity play a role in the pathogenesis of NIDDM and obesity,hypertension and hyperlipoproteinemia are the most important risk factors in the NIDDM etiology.The community NIDDM intervention should be stressed on the diet,exercise,control of body weight and blood pressure,and prevention propagation to the common and special risk factors of different population groups.