肝损伤后溶酶体和酸性磷酸酶活性改变和蓝靛果的作用

Changes of lysosome and acid phosphatase activity after liver lesion and study of effects of lonicera edulis

[目的 ]探讨蓝靛果对四氯化碳所致小鼠急性肝损伤的保护作用 .[方法 ]用四氯化碳造成小鼠肝细胞损伤模型 ,观察肝细胞中溶酶体及酸性磷酸酶活性的变化 .[结果 ]实验组与对照组相比 ,肝细胞中溶酶体数量减少 ,酸性磷酸酶活性降低 .[结论 ]蓝靛果对肝细胞具有一定的保护作用 .

OBJECTIVE? It was studied that the protective effects of lonicera edulis for acute liver lesion of mice induced by carbon tetrechloride. ?METHODS? The model of liver lesion of mice was induced by carbon tetrachloride,and the changes of lysosome and acid phosphatase of liver cells were observed. ?RESULTS? Compared to control group, the lysosome amount and the acid phosphatase activity of liver cells decreased in experimental group. ?CONCLUSION? The lonicera edulis has a protective effects for liver cells.