高血压患者左室功能状态与心率变异关系的研究

A study on the relationship between left ventricular function and HRV in hypertension

目的:比较高血压患者与正常对照组左室功能及心率变异的相关性。方法:用超声心动图的方法测量左室收缩功能及舒张功能指标 ;用短程心率变异 (HRV)检测时域及频域各指标。结果 :高血压患者 HRV时域及频域指标均有不同程度的改变 ,低频 (L F)与高频 (HF)比值高血压组与正常组比较差异显著 (P<0 .0 1) ;HRV时域与频域指标与左室收缩功能指标之间几乎均无相关性 (P>0 .0 5 ) ;而与左室舒张功能指标间有一定的相关性 (P<0 .0 5或 P <0 .0 1)。结论:(1)高血压患者 HRV、左室舒张功能损害出现较早。 (2 ) HRV与左室功能状态等的关系研究值得深入探讨 ,并做出合理解释 。

Objective: To elucidate the degree of heart damage by evaluation of left ventricular function, HRV and its relationship. Methods: 42 cases of essential hypertensives(EH) and 46 normal persons were measured by echocardiography in order to obtain their heart function indexes (the systolic function and diastolic function indexes). Simultaneously, they were measured on short term HRV in order to obtain their Time Domain and Frequency Domain indexes. Results: The results of this study showed as follows: (1) The indexes of Time Domain and Frequency Domain of HRV changed in some degrees; (2)The indexes between Time Domain and Frequency Domain showed significant positive correlation (P<0.01); (3)The indexes between HRV and left ventricular systolic function revealed no correlation (P>0.05); The indexes between HRV (indexes of Time Domain and Frequency Domain) and left ventricular diastolic function showed correlation in some degrees (P<0.05 or P<0.01). Conclusions: (1)The damage of HRV and left ventricular diastolic function appeared in the early phase of hypertension. (2)The relationship between HRV and left ventricular function should be further studied and should be reasonablely explained. It may be helpful to therapy of hypertension.