摘要
目的探讨白细胞介素（ｉｎｔｅｒｌｅｕｌｋｉｎ）６、８在急性白血病中的意义。方法采用放射免疫法测定细胞因子成员中ＩＬ－６和ＩＬ－８在急性白血病治疗前和治疗后获得完全缓解患者及正常人血清中表达及其意义。结果ＡＬ治疗前和ＡＬ获ＣＲ后患者的外周血血清ＩＬ－６和ＩＬ－８水平明显低于正常对照组。结论ＡＬ发病与免疫应答功能降低有关。
Objective To investigate the pathogenic significance of IL-6 and IL-8 in acute leukemia (AL). Methods Serum IL-6 and IL-8 were tested using the radioimmunological method in the normal controls and the patients with acute leukemia before and after treatment, including complete recovered (CR) patients. Results The level of serum IL-6 and IL-8 in the patients with AL before and after treatment with complete recovered were significant lower than that in normal controls. Conclusion The reduction of serum IL-6 and IL-8 in the patients with An before and after treatment suggested that the pathogenesis of AL may be associated to immunological dysfunction.
出处
《贵州医药》
CAS
2001年第7期590-591,共2页
Guizhou Medical Journal
