心脏肌钙蛋白Ⅰ在急性心肌梗死中的临床意义

Significance of cardiac troponin Ⅰ levels after acute myocardial infarction

目的 :探讨心脏肌钙蛋白 (c Tn )在急性心肌梗死 (AMI)中的临床意义。方法 :6 0例 AMI,其中 Q波型 AMI42例 ,非 Q波型 AMI18例 ,分别于入院即刻、 2 4小时、 72小时、 7天抽血 ,测定 c Tn 、CK- MB,随访半年。结果 :(1) c Tn 阳性率在 AMI即刻、 2 4小时、 72小时、 7天的 Q波型 AMI和非 Q波型 AMI依次分别为2 3.8% ,10 0 % ,90 .48% ,2 6 .19% ;11.11% ,77.78% ,5 5 .5 6 % ,16 .6 1%。Q波型 AMI的 c Tn 水平明显依次高于 CK- MB的 11.9%、 90 .48%、 11.97%、 0 % ;(2 )第 7天持续阳性的 14例中 ,4例死于心脏骤停 ,5例发生心衰 ,5例发生心绞痛。结论 :(1) AMI后 2 4小时 c Tn 阳性率高于 CK- MB;(2 ) c Tn

Objective:To asses the clinical significance of cardiac troponin Ⅰ(cTnⅠ) levels after acute myocardial infarction(AMI).Methods:Blood sample of cTnⅠ and CK\|MB take at immediately,day 1、2、3 and 7th after hospitalization were measured in 60 patient with AMI.Results:(1)The positive rates of cTnⅠ in AMI patient with Q wave and non Q wave at immediately and 2、3、7th day after hospitalization were 23 8%,100%,90 48%,26 19%;11 11%,77 78%,55 56%,16 61% respectively,positive rates of cTnⅠ in AMI patients with Q were significantly higher than 11 9%、90 48%、11 97%、0% of CB\|MB( P <0 01);(2)There were 14 patients with AMI their cTnⅠ were still positive at 7th day.In which 4 patients dead in heart event,5 patients happened heart failure,5 patients appeared angina.Conclusion:(1)The positive rates of cTnⅠ in AMI patients with Q wave were significantly higher than that of CK\|MB in 24h;(2) Positive of cTnⅠ last to 7th day after hospitalization in AMI patients suggest that prognosis of patients are bed.