类异戊二烯非甲羟戊酸代谢途径的分子生物学研究进展

Advance on molecular biology of isoprenoids non-mevalonate pathway

近期发现的类异戊二烯非甲羟戊酸代谢途径是类异戊二烯化合物生物合成的另一途径。文章对该代谢途径的分子生物学研究进展进行了综述。重点介绍非甲羟戊酸代谢途径的发现和 5 -磷酸脱氧木糖合成酶、5 -磷酸脱氧木糖还原异构酶。

Non-mevalonate pathway of isoprenoids found recently is anothe r isoprenoid biosynthesis pathway.We summarized the advances in molecular biology of the new pathway.It was emphasized that the discovery of non-mevalonate pathway and the molecular clones of 1-deoxy-D-xylulose-phosphate synthase(DXS),1-deoxy-D-xylulose 5-phosphate reductoisomerase(DXR),isoprenyl diphosphate synthase(IPPS).The discovery of non-mevalonate pathway has great applications on agricultural and pharmaceutical areas.