影响酵母细胞麦角固醇的发酵控制参数的分析

Analysis of Parameters for Optimum of Ergosterol Fermentation

研究了麦角固醇发酵过程中的参数。比较了溶氧、OUR、pH和残糖浓度与酿酒酵母的生物量和麦角固醇含量的关系 ,并研究了这些参数之间的内在联系。研究表明 ,溶氧能比较准确地反映酵母的生长状况 ,是发酵过程中的一个较好的控制参数。将溶氧控制在 12 %左右能有效提高单位体积发酵液中的麦角固醇的产量。

Parameters in the process of ergoterol fermentation are studied. The relationship between biomass, ergosterol content in Saccharomyces cerevisiae and parameters such as DO , pH, OUR , glucose concentration, are discussed. Because of its good manipulation in yeast fermentation process, DO can thus serve as an effective control parameter. DO at about 12% (±1%) can enhance the total yield of ergosterol considerably.