高频电汽化切除并注射THP治疗浅表膀胱癌18例

Transurethral Electro-Vaporization Combined with Mucomembranous and Intravesical Administration or THP for the Treatment of Superficial Bladder Tumor (Report of 18 Cases)

目的 :探讨高频电汽化切除后粘膜下注射及膀胱内灌注抗癌药物治疗浅表膀胱肿瘤的效果。方法 :经尿道高频电汽化膀胱肿瘤、肿瘤周围粘膜下和基底部注射盐酸吡柔比星 (THP) ,术后间断膀胱内灌注THP。结果 :本组 18例浅表膀胱肿瘤 ,术中、术后均无输血 ,无膀膀穿孔 ,未引起组织坏死。术后随访 (6 - 15 )月 ,未引起骨髓抑制 ,未见肿瘤复发。结论 :此方法操作简单、安全、恢复快 ,并发症低。粘膜下注射并膀胱内灌注抗癌药物重点部位突出 ,药液扩散均匀 ,既可杀灭存留的肿瘤细胞 ,又对微小癌灶产生毒性作用 。

Objective:To investigate the effect of transurethral electro-vaporization combined with muconembranous and intravesical administration of piraubicin hydrochloride (THP) for the treatment of bladder tumor.Methods:The tumor were ablated by transurethral electro-vaporiztation ,and then THP were inject into mucomymb around tumors.After operation operation,THP were perfused into urinary bladder cavity periodically results the operations were successful in all 18 cases of bladder without transfusion and vesical perforation Tumor did not recurrence and depressed marrow were not found in all cases in following6-15 months.Conclusion:THP could destroy the rudimental cells of tumor by mucomim branous and intravesical administration completely Transuerthral electro-vaporization combined with mucomembranous and intravesical administration of THP was effective on bodder tumor,characterized by simplify and less complicution.\;